Using linkers to investigate the spatial separation of the conserved nucleotides A9 and G12 in the hammerhead ribozyme.

Using linkers to investigate the spatial separation of the conserved nucleotides A9 and G12 in the hammerhead ribozyme.

Two series of hammerhead-derived ribozymes, or 'minizymes', in which helix II has been replaced by linkers of non-nucleotidic moieties, have been synthesised by solid-phase methods. In the first series, the minizymes had linkers containing one, two, three, four or five repeated units of ph...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Hendry, P, Moghaddam, M, McCall, M, Jennings, P, Ebel, S, Brown, T
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	1994

Míreanna comhchosúla

OPTIMIZING HAMMERHEAD RIBOZYMES FOR USE AGAINST HIV IN-VIVO
de réir: Thompson, S, et al.
Foilsithe / Cruthaithe: (1995)

New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes.
de réir: El-Sagheer, A, et al.
Foilsithe / Cruthaithe: (2010)

Selective cleavage of AChR cRNAs harbouring mutations underlying the slow channel myasthenic syndrome by hammerhead ribozymes.
de réir: Abdelgany, A, et al.
Foilsithe / Cruthaithe: (2005)

Hammerhead ribozyme-mediated silencing of the mutant fibrillin-1 of tight skin mouse: insight into the functional role of mutant fibrillin-1.
de réir: Menon, R, et al.
Foilsithe / Cruthaithe: (2006)

Hammerhead ribozyme specifically inhibits vascular endothelial growth factor gene expression in a human hepatocellular carcinoma cell line.
de réir: Morino, F, et al.
Foilsithe / Cruthaithe: (2000)

Nucleotide recognition and metal ion requirements of an RNA ligase ribozyme
de réir: Glasner, Margaret E. (Margaret Elyn), 1972-
Foilsithe / Cruthaithe: (2005)

Ribozyme Mediated gRNA Generation for In Vitro and In Vivo CRISPR/Cas9 Mutagenesis
de réir: Lee, Raymond Teck Ho, et al.
Foilsithe / Cruthaithe: (2016)

Hammerhead ribozymes reduce central nervous system (CNS)-derived neuronal nitric oxide synthase messenger RNA in a human cell line.
de réir: Maniotis, D, et al.
Foilsithe / Cruthaithe: (2002)

Close to the edge : finding the Hammerhead Bar
de réir: Nowell, Gregory
Foilsithe / Cruthaithe: (2013)

[RNA polymerase ribozymes]
de réir: Lawrence, Michael S. (Michael Scott), 1975-
Foilsithe / Cruthaithe: (2008)

Ribozymes and RNA catalysis /
de réir: Lilley, David M. J. David Malcolm James, 1948-, et al.
Foilsithe / Cruthaithe: (2008)

Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding.
de réir: Matsuo, M, et al.
Foilsithe / Cruthaithe: (2002)

The crystal structure of d(G-G-G-G-C-C-C-C). A model for poly(dG).poly(dC).
de réir: McCall, M, et al.
Foilsithe / Cruthaithe: (1985)

Searching for ribozymes with new and improved properties
de réir: Curtis, Edward A. (Edward Arthur)
Foilsithe / Cruthaithe: (2007)

Ribozymes as therapeutic tools for genetic disease.
de réir: Phylactou, L, et al.
Foilsithe / Cruthaithe: (1998)

Computational approaches to the identification of ribozyme target sites.
de réir: James, W, et al.
Foilsithe / Cruthaithe: (1997)

Engineering RNA logic with synthetic splicing ribozymes
de réir: Che, Austin, 1979-
Foilsithe / Cruthaithe: (2009)

The use of ribozymes in gene therapy approaches to AIDS.
de réir: James, W
Foilsithe / Cruthaithe: (1998)

Shifts in the habitat suitability for large hammerhead sharks under climate change
de réir: Santos, CP, et al.
Foilsithe / Cruthaithe: (2024)

Bioscaffold-Linker
de réir: Mina, Petros, et al.
Foilsithe / Cruthaithe: (2009)

Analysis and design of hammerhead bridge pier using a strut and tie method
de réir: Ahyat, Abdul Kadir
Foilsithe / Cruthaithe: (2005)

Kinetic barriers to folding in the Tetrahymena group I ribozyme
de réir: Rook, Martha S. (Martha Sanderson), 1970-
Foilsithe / Cruthaithe: (2009)

Ribozyme-mediated trans-splicing of a trinucleotide repeat.
de réir: Phylactou, L, et al.
Foilsithe / Cruthaithe: (1998)

Ribozymes and siRNA for the treatment of diseases of the nervous system.
de réir: Wood, M, et al.
Foilsithe / Cruthaithe: (2003)

Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro.
de réir: Crisell, P, et al.
Foilsithe / Cruthaithe: (1993)

Earth science mapping for planning, development, and conservation /
de réir: McCall, G. J. H. (Gerald Joseph Home), 1920-, et al.
Foilsithe / Cruthaithe: (1989)

An extensible dynamic linker for C++
de réir: Vemulapati, Murali Krishna
Foilsithe / Cruthaithe: (2007)

Asymmetric linker-mediated vitrimers
de réir: Zeng, Wu
Foilsithe / Cruthaithe: (2022)

Non-classical propositional calculi
de réir: McCall, S, et al.
Foilsithe / Cruthaithe: (1964)

Ribozyme-based insulator parts buffer synthetic circuits from genetic context
de réir: Lou, Chunbo, et al.
Foilsithe / Cruthaithe: (2014)

PROFOUND INHIBITION OF HIV-1 REPLICATION IN CULTURED-CELLS BY RIBOZYMES - CONVERSE CORRELATION WITH INVITRO ACTIVITY
de réir: James, W, et al.
Foilsithe / Cruthaithe: (1993)

Community profiling of the intestinal microbial community of juvenile Hammerhead Sharks (Sphyrna lewini) from the Rewa Delta, Fiji
de réir: Juste-Poinapen, Natacha M. S., et al.
Foilsithe / Cruthaithe: (2019)

Seasonal movements and habitat use of juvenile smooth hammerhead sharks in the western North Atlantic Ocean and significance for management
de réir: Logan, RK, et al.
Foilsithe / Cruthaithe: (2020)

Evaluating Performance of Different RNA Secondary Structure Prediction Programs Using Self-cleaving Ribozymes
de réir: Qi, F, et al.
Foilsithe / Cruthaithe: (2024)

Photolabile linkers for solid-phase synthesis
de réir: Mikkelsen, Remi J. T., et al.
Foilsithe / Cruthaithe: (2020)

Cross-cultural analysis on technology linkers.
de réir: Lim, Ai Leng., et al.
Foilsithe / Cruthaithe: (2008)

Bisintercalators of DNA with a rigid linker in an extended configuration.
de réir: Mullins, S, et al.
Foilsithe / Cruthaithe: (1992)

Recognition of CpG island chromatin by KDM2A requires direct and specific interaction with linker DNA.
de réir: Zhou, J, et al.
Foilsithe / Cruthaithe: (2012)

Recognition of CpG island chromatin by KDM2A requires direct and specific interaction with linker DNA
de réir: Zhou, J, et al.
Foilsithe / Cruthaithe: (2012)

A linker protein from a red-type pyrenoid phase separates with Rubisco via oligomerizing sticker motifs
de réir: Oh, Zhen Guo, et al.
Foilsithe / Cruthaithe: (2024)