Solution- and solid-state NMR studies of GPCRs and their ligands.

Solution- and solid-state NMR studies of GPCRs and their ligands.

Show other versions (1)

G protein-coupled receptors (GPCRs) represent one of the major targets of new drugs on the market given their roles as key membrane receptors in many cellular signalling pathways. Structure-based drug design has potential to be the most reliable method for novel drug discovery. Unfortunately, GPCR-l...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Tapaneeyakorn, S, Goddard, A, Oates, J, Willis, C, Watts, A
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2011

Eitemau Tebyg

Solution- and solid-state NMR studies of GPCRs and their ligands
gan: Tapaneeyakorn, S, et al.
Cyhoeddwyd: (2011)

Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor.
gan: Grobner, P, et al.
Cyhoeddwyd: (1998)

Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor.
gan: Williamson, P, et al.
Cyhoeddwyd: (1998)

Solid state NMR studies of ligand conformations in the binding sites of ion translocating APTases
gan: Watts, J, et al.
Cyhoeddwyd: (1999)

Solid state NMR studies of ligand dynamics and conformations is the binding sites of the gastric H+/K+-ATPase
gan: Watts, J, et al.
Cyhoeddwyd: (2000)

Ligands and Beyond: Mechanosensitive Adhesion GPCRs
gan: Hsi-Hsien Lin, et al.
Cyhoeddwyd: (2022-02-01)

G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy.
gan: Ding, X, et al.
Cyhoeddwyd: (2013)

Special Issue “GPCRs: Ligands and beyond 2022”
gan: Erika Cione, et al.
Cyhoeddwyd: (2022-05-01)

Protein-lipid interactions is bacteriorhodopsin studied by solid state NMR
gan: Mason, J, et al.
Cyhoeddwyd: (2000)

Preface: Solid-state NMR on biological systems
gan: Watts, A
Cyhoeddwyd: (2004)

Recent developments in biomolecular solid-state NMR
gan: Higman, V, et al.
Cyhoeddwyd: (2012)

Solid-state NMR approaches for studying the interaction of peptides and proteins with membranes
gan: Watts, A
Cyhoeddwyd: (1998)

Enantioselective syntheses of alpha-Fmoc-Pbf-[2-(13)C]-L-arginine and Fmoc-[1,3-(13)C2]-L-proline and Incorporation into the neurotensin receptor 1 ligand, NT(8-13).
gan: Song, C, et al.
Cyhoeddwyd: (2009)

A Potential Blueprint for the Design of Biased Ligands for Aminergic GPCRs
gan: Marcel Bermudez
Cyhoeddwyd: (2022-11-01)

Utilizing Peptide Ligand GPCRs to Image and Treat Pancreatic Cancer
gan: Gail L. Matters, et al.
Cyhoeddwyd: (2018-06-01)

Membrane protein structure determination by solid state NMR.
gan: Watts, A, et al.
Cyhoeddwyd: (1999)

Structural resolution of ligand-receptor interactions in functional, membrane-embedded receptors and proteins using novel, non-perturbing solid-state NMR methods
gan: Watts, A
Cyhoeddwyd: (1999)

NMR of drugs and ligands bound to membrane receptors.
gan: Watts, A
Cyhoeddwyd: (1999)

Structural descriptions of ligands in their binding site of integral membrane proteins at near physiological conditions using solid-state NMR
gan: Watts, A, et al.
Cyhoeddwyd: (1998)

Solid state nuclear magnetic resonance (ss-NMR) of ligand protein interactions in the nicotinic acetylcholine receptor (nAChR)
gan: Williamson, P, et al.
Cyhoeddwyd: (1996)

Structural and functional studies of the nicotinic acetylcholine receptor by solid-state NMR.
gan: Williamson, P, et al.
Cyhoeddwyd: (2004)

What Makes GPCRs from Different Families Bind to the Same Ligand?
gan: Kwabena Owusu Dankwah, et al.
Cyhoeddwyd: (2022-06-01)

Solid-state NMR in drug design and discovery for membrane-embedded targets.
gan: Watts, A
Cyhoeddwyd: (2005)

Paramagnetic Solid-State NMR Study of Solid Solutions of Cobaltocene with Ferrocene and Nickelocene
gan: Gabrielle E. Harmon-Welch, et al.
Cyhoeddwyd: (2024-08-01)

A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs
gan: Ambrose Plante, et al.
Cyhoeddwyd: (2019-06-01)

Solid-state O-17 NMR of amino acids
gan: Pike, K, et al.
Cyhoeddwyd: (2004)

Structure determination of membrane-associated amyloid-beta-peptide by solid state NMR
gan: Groebner, G, et al.
Cyhoeddwyd: (2000)

Membrane protein structure determination using solid-state NMR.
gan: Watts, A, et al.
Cyhoeddwyd: (2004)

Elucidating ligand-bound structures of membrane proteins using solid-state NMR spectroscopy
gan: Elkins, Matthew Ryan, et al.
Cyhoeddwyd: (2020)

Use of solid-state H-2 NMR for studying protein-lipid interactions at emulsion interfaces
gan: Areas, J, et al.
Cyhoeddwyd: (1997)

Interaction of a type II myosin with biological membranes studied by 2H solid state NMR.
gan: Arêas, J, et al.
Cyhoeddwyd: (1998)

Solid-state NMR of polymers /
gan: 356807 Mirau, Peter A.
Cyhoeddwyd: (2001)

Solid state NMR for chemists/
gan: 448055 Fyfe, Colin A.
Cyhoeddwyd: (1983)

Structural studies of prospholamban using solid-state magic-angle spinning (MAS) NMR methods.
gan: Ahmed, Z, et al.
Cyhoeddwyd: (2000)

Structure determination of the cyclohexene ring of retinal in bacteriorhodopsin by solid-state deuterium NMR.
gan: Ulrich, A, et al.
Cyhoeddwyd: (1992)

Membrane protein structure: the contribution and potential of novel solid state NMR approaches.
gan: Watts, A, et al.
Cyhoeddwyd: (1995)

Expression of mammalian GPCRs in <it>C. elegans </it>generates novel behavioural responses to human ligands
gan: Jansen Gert, et al.
Cyhoeddwyd: (2006-07-01)

The antimicrobial action of PGLa - Only based on electrostatic interactions? A solid state NMR study.
gan: Hickel, A, et al.
Cyhoeddwyd: (2004)

Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR.
gan: Williamson, P, et al.
Cyhoeddwyd: (2002)

Recent contributions from solid-state NMR to the understanding of membrane protein structure and function
gan: Judge, P, et al.
Cyhoeddwyd: (2011)