Solution- and solid-state NMR studies of GPCRs and their ligands.

G protein-coupled receptors (GPCRs) represent one of the major targets of new drugs on the market given their roles as key membrane receptors in many cellular signalling pathways. Structure-based drug design has potential to be the most reliable method for novel drug discovery. Unfortunately, GPCR-l...

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Principais autores: Tapaneeyakorn, S, Goddard, A, Oates, J, Willis, C, Watts, A
Formato: Journal article
Idioma:English
Publicado em: 2011