The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei.

The Burkholderia pseudomallei K96243 genome encodes six type VI secretion systems (T6SSs), but little is known about the role of these systems in the biology of B. pseudomallei. In this study, we purified recombinant Hcp proteins from each T6SS and tested them as vaccine candidates in the BALB/c mou...

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Những tác giả chính: Burtnick, M, Brett, P, Harding, S, Ngugi, SA, Ribot, W, Chantratita, N, Scorpio, A, Milne, T, Dean, R, Fritz, D, Peacock, S, Prior, J, Atkins, T, Deshazer, D
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2011