Unique acquisition of cytotoxic T-lymphocyte escape mutants in infant human immunodeficiency virus type 1 infection.

Unique acquisition of cytotoxic T-lymphocyte escape mutants in infant human immunodeficiency virus type 1 infection.

The role of cytotoxic T-lymphocyte (CTL) escape in rapidly progressive infant human immunodeficiency virus type 1 (HIV-1) infection is undefined. The data presented here demonstrate that infant HIV-1-specific CTL can select for viral escape variants very early in life. These variants, furthermore, m...

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Autores principales: Pillay, T, Zhang, H, Drijfhout, J, Robinson, N, Brown, H, Khan, M, Moodley, J, Adhikari, M, Pfafferott, K, Feeney, M, St John, A, Holmes, E, Coovadia, H, Klenerman, P, Goulder, P, Phillips, R
Formato: Journal article
Lenguaje:English
Publicado: 2005

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