The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

Lignende værker

• Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant: implications for disease susceptibility to Creutzfeldt-Jakob disease.
  af: Tahiri-Alaoui, A, et al.
  Udgivet: (2004)
• Inter-oligomer interactions of the human prion protein are modulated by the polymorphism at codon 129.
  af: Gerber, R, et al.
  Udgivet: (2008)
• A novel form of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report
  af: Bilbao Miren J, et al.
  Udgivet: (2010-10-01)
• Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.
  af: Rhie, A, et al.
  Udgivet: (2003)
• Rapid formation of amyloid from alpha-monomeric recombinant human PrP in vitro.
  af: Tahiri-Alaoui, A, et al.
  Udgivet: (2005)