Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.

BACKGROUND and AIMS: Toll-like receptors (TLR) are innate immune receptors involved in recognition of the intestinal microflora; they are expressed by numerous cell types in the intestine, including epithelial cells, myeloid cells, and lymphocytes. Little is known about the relative contributions o...

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Hlavní autoři: Asquith, M, Boulard, O, Powrie, F, Maloy, K
Médium: Journal article
Jazyk:English
Vydáno: 2010