Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis

<strong>Background</strong> Plasmodium falciparum infections with slow parasite clearance following artemisinin-based therapies are widespread in the Greater Mekong Subregion. A molecular marker of the slow clearance phenotype has been identified: single genetic changes within the propel...

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Main Authors: Ashley, E, Dhorda, M, Dondorp, A, Fanello, C, Guérin, P, Humphreys, G, Kennon, K, Mayxay, M, Nosten, F, Phyo, A, Sibley, C, Sondo, P, Stepniewska, K, White, N, Woodrow, C, WWARN K13 Genotype-Phenotype Study Group
格式: Journal article
语言:English
出版: BioMed Central 2019