RIGorous detection: exposing virus through RNA sensing.

Virus infection in mammals elicits a variety of defense responses that are initiated by signals from virus-sensing receptors expressed by the host. These receptors include the ubiquitously expressed RIG-I-like receptor (RLR) family of RNA helicases. RLRs are cytoplasmic proteins that act in cell-int...

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Bibliographic Details
Main Authors: Rehwinkel, J, Reis e Sousa, C
Format: Journal article
Language:English
Published: 2010