An ultrastructural study of the phagocytosis of Burkholderia pseudomallei.
Burkholderia pseudomallei causes melioidosis and is believed to be an intracellular pathogen in human and animal disease. The uptake of B. pseudomallei by mouse peritoneal macrophages and cells in tissue culture was examined by electron microscopy. In all the systems studied B. pseudomallei were pha...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1998
|
| _version_ | 1797094662687686656 |
|---|---|
| author | Harley, V Dance, D Tovey, G McCrossan, M Drasar, B |
| author_facet | Harley, V Dance, D Tovey, G McCrossan, M Drasar, B |
| author_sort | Harley, V |
| collection | OXFORD |
| description | Burkholderia pseudomallei causes melioidosis and is believed to be an intracellular pathogen in human and animal disease. The uptake of B. pseudomallei by mouse peritoneal macrophages and cells in tissue culture was examined by electron microscopy. In all the systems studied B. pseudomallei were phagocytosed and apparently inhibited the normal processes of intracellular killing. Destruction of the phagosome membrane occurred and the bacteria escaped into the cytoplasm. |
| first_indexed | 2024-03-07T04:17:06Z |
| format | Journal article |
| id | oxford-uuid:c9c1dd30-53b7-4260-9bf8-462517461e0b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:17:06Z |
| publishDate | 1998 |
| record_format | dspace |
| spelling | oxford-uuid:c9c1dd30-53b7-4260-9bf8-462517461e0b2022-03-27T07:01:54ZAn ultrastructural study of the phagocytosis of Burkholderia pseudomallei.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c9c1dd30-53b7-4260-9bf8-462517461e0bEnglishSymplectic Elements at Oxford1998Harley, VDance, DTovey, GMcCrossan, MDrasar, BBurkholderia pseudomallei causes melioidosis and is believed to be an intracellular pathogen in human and animal disease. The uptake of B. pseudomallei by mouse peritoneal macrophages and cells in tissue culture was examined by electron microscopy. In all the systems studied B. pseudomallei were phagocytosed and apparently inhibited the normal processes of intracellular killing. Destruction of the phagosome membrane occurred and the bacteria escaped into the cytoplasm. |
| spellingShingle | Harley, V Dance, D Tovey, G McCrossan, M Drasar, B An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. |
| title | An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. |
| title_full | An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. |
| title_fullStr | An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. |
| title_full_unstemmed | An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. |
| title_short | An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. |
| title_sort | ultrastructural study of the phagocytosis of burkholderia pseudomallei |
| work_keys_str_mv | AT harleyv anultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT danced anultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT toveyg anultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT mccrossanm anultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT drasarb anultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT harleyv ultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT danced ultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT toveyg ultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT mccrossanm ultrastructuralstudyofthephagocytosisofburkholderiapseudomallei AT drasarb ultrastructuralstudyofthephagocytosisofburkholderiapseudomallei |