Use of lipoteichoic acid-T for pleurodesis in malignant pleural effusion: a phase I toxicity and dose-escalation study.

BACKGROUND: Bacterial infection of the pleural space often causes adherence of the pleural membranes by fibrous tissue, probably mediated by inflammation initiated by bacterial cell-wall motifs, including lipoteichoic acid-T (LTA-T). We postulated that therapeutically administered LTA-T might produc...

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Hlavní autoři: Rahman, N, Davies, H, Salzberg, M, Truog, P, Midgely, R, Kerr, D, Clelland, C, Hedley, E, Lee, Y, Davies, R
Médium: Journal article
Jazyk:English
Vydáno: 2008