Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial.

Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial.

For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis efficacy. Smaller chest tubes may be less painful than larger tubes, but efficacy in pleurodesis has not been proven.To assess the effect of chest tube size and...

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Bibliographic Details
Main Authors: Rahman, N, Pepperell, J, Rehal, S, Saba, T, Tang, A, Ali, N, West, A, Hettiarachchi, G, Mukherjee, D, Samuel, J, Bentley, A, Dowson, L, Miles, J, Ryan, C, Yoneda, K, Chauhan, A, Corcoran, J, Psallidas, I, Wrightson, J, Hallifax, R, Davies, H, Lee, Y, Dobson, M, Hedley, E, Seaton, D, Russell, N, Chapman, M, McFadyen, B, Shaw, R, Davies, R, Maskell, N, Nunn, A, Miller, R
Format: Journal article
Language:English
Published: American Medical Association 2015

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