Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4
CHD4, the core subunit of the Nucleosome Remodelling and Deacetylase (NuRD) complex, is a chromatin remodelling ATPase that, in addition to a helicase domain, harbors tandem plant homeo finger and chromo domains. By using a panel of domain constructs we dissect their roles and demonstrate that DNA b...
Main Authors: | Morra, R, Lee, B, Shaw, H, Tuma, R, Mancini, E |
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Format: | Journal article |
Language: | English |
Published: |
2012
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