Exploiting the defensive sugars of HIV-1 for drug and vaccine design
The sustained effort towards developing an antibody vaccine against HIV/AIDS has provided much of our understanding of viral immunology. It is generally accepted that one of the main barriers to antibody neutralization of HIV is the array of protective structural carbohydrates that covers the antige...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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Nature Research
2007
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| _version_ | 1826296521058942976 |
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| author | Scanlan, C Offer, J Zitzmann, N Dwek, R |
| author_facet | Scanlan, C Offer, J Zitzmann, N Dwek, R |
| author_sort | Scanlan, C |
| collection | OXFORD |
| description | The sustained effort towards developing an antibody vaccine against HIV/AIDS has provided much of our understanding of viral immunology. It is generally accepted that one of the main barriers to antibody neutralization of HIV is the array of protective structural carbohydrates that covers the antigens on the virus's surface. Intriguingly, however, recent findings suggest that these carbohydrates, which have evolved to protect HIV and promote its transmission, are also attractive therapeutic targets. |
| first_indexed | 2024-03-07T04:17:37Z |
| format | Journal article |
| id | oxford-uuid:c9ecb654-9f7e-4df8-a61c-f60f9af76d17 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:17:37Z |
| publishDate | 2007 |
| publisher | Nature Research |
| record_format | dspace |
| spelling | oxford-uuid:c9ecb654-9f7e-4df8-a61c-f60f9af76d172022-03-27T07:03:28ZExploiting the defensive sugars of HIV-1 for drug and vaccine designJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c9ecb654-9f7e-4df8-a61c-f60f9af76d17EnglishSymplectic Elements at OxfordNature Research2007Scanlan, COffer, JZitzmann, NDwek, RThe sustained effort towards developing an antibody vaccine against HIV/AIDS has provided much of our understanding of viral immunology. It is generally accepted that one of the main barriers to antibody neutralization of HIV is the array of protective structural carbohydrates that covers the antigens on the virus's surface. Intriguingly, however, recent findings suggest that these carbohydrates, which have evolved to protect HIV and promote its transmission, are also attractive therapeutic targets. |
| spellingShingle | Scanlan, C Offer, J Zitzmann, N Dwek, R Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
| title | Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
| title_full | Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
| title_fullStr | Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
| title_full_unstemmed | Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
| title_short | Exploiting the defensive sugars of HIV-1 for drug and vaccine design |
| title_sort | exploiting the defensive sugars of hiv 1 for drug and vaccine design |
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