Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria

Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria

Čájet eará veršuvnnaid (1)

Aims To investigate the population pharmacokinetics of the antimalarial halofantrine (HF) in healthy volunteers and patients with symptomatic falciparum malaria. Methods Healthy volunteer data were obtained from six volunteers who received three different doses of HF (250, 500 and 1000 mg) after an...

Bibliográfalaš dieđut
Váldodahkkit:	Klein, K, Aarons, L, Ter Kuile, F, Nosten, F, White, N, Edstein, MD, Teja-Isavadharm, P
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2012

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Erratum: Plasmodium falciparum malaria (Journal of Infectious Diseases (October 1994) 170 (971-977))
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