Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria

Aims To investigate the population pharmacokinetics of the antimalarial halofantrine (HF) in healthy volunteers and patients with symptomatic falciparum malaria. Methods Healthy volunteer data were obtained from six volunteers who received three different doses of HF (250, 500 and 1000 mg) after an...

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Autori principali: Klein, K, Aarons, L, Ter Kuile, F, Nosten, F, White, N, Edstein, MD, Teja-Isavadharm, P
Natura: Journal article
Lingua:English
Pubblicazione: 2012