AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Dummer, R, Robert, C, Chapman, P, Sosman, J, Middleton, M, Bastholt, L, Kemsley, K, Cantarini, M, Morris, C, Kirkwood, J
التنسيق:	Journal article
منشور في:	2008

DOC-MEK: A double-blind randomized phase II trial of docetaxel with or without selumetinib (AZD6244; ARRY-142886) in wt BRAF advanced melanoma
حسب: Gupta, A, وآخرون
منشور في: (2013)

Author Correction: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer
حسب: Jin-Hang Gao, وآخرون
منشور في: (2022-03-01)

MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib
حسب: Takahashi, O, وآخرون
منشور في: (2009)

Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma.
حسب: Kirkwood, J, وآخرون
منشور في: (2012)

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors
حسب: Leijen, S, وآخرون
منشور في: (2011)

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors.
حسب: Leijen, S, وآخرون
منشور في: (2011)

TMZ-BioShuttle – a reformulated Temozolomide
حسب: Waldemar Waldeck, Manfred Wiessler, Volker Ehemann, Ruediger Pipkorn, Herbert Spring, Juergen Debus, Bernd Didinger, Gabriele Mueller, Joerg Langowski, Klaus Braun
منشور في: (2008-01-01)

Radiosensitization of Glioma Cells by Temozolomide (TMZ): A Colony Formation Assay
حسب: Somayyeh Babaloui, وآخرون
منشور في: (2022-02-01)

Targeting ERK1/2 activation and proliferation in human primary schwannoma cells with MEK1/2 inhibitor AZD6244
حسب: Sylwia Ammoun, وآخرون
منشور في: (2010-01-01)

Temozolomide (TMZ) in the Treatment of Glioblastoma Multiforme—A Literature Review and Clinical Outcomes
حسب: Marcin Jezierzański, وآخرون
منشور في: (2024-07-01)

Resistance to Selumetinib (AZD6244) in Colorectal Cancer Cell Lines is Mediated by p70S6K and RPS6 Activation
حسب: Silvina Grasso, وآخرون
منشور في: (2014-10-01)

miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM)
حسب: Zongze He, وآخرون
منشور في: (2022-10-01)

Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis
حسب: Jun-Hai Tang, وآخرون
منشور في: (2019-12-01)

Concomitant treatment of brain metastasis with Whole Brain Radiotherapy [WBRT] and Temozolomide [TMZ] is active and improves Quality of Life
حسب: Montella Liliana, وآخرون
منشور في: (2007-01-01)

Long-term Temozolomide Treatment Induces Marked Amino Metabolism Modifications and an Increase in TMZ Sensitivity in Hs683 Oligodendroglioma Cells
حسب: Delphine Lamoral-Theys, وآخرون
منشور في: (2010-01-01)

Co-administration of temozolomide (TMZ) and the experimental therapeutic targeting miR-10b, profoundly affects the tumorigenic phenotype of human glioblastoma cells
حسب: Ming Chen, وآخرون
منشور في: (2023-06-01)

Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol
حسب: Paul Lesueur, وآخرون
منشور في: (2019-03-01)

Transcriptomic analysis identifies the neuropeptide cortistatin (CORT) as an inhibitor of temozolomide (TMZ) resistance by suppressing the NF-κB-MGMT signaling axis in human glioma
حسب: Zongze He, وآخرون
منشور في: (2024-05-01)

TRPC5 mediates TMZ resistance in TMZ-resistant glioblastoma cells via NFATc3-P-gp pathway
حسب: Yan Zou, وآخرون
منشور في: (2021-12-01)

Randomized trial of the combination of lomeguatrib and temozolomide compared with temozolomide alone in chemotherapy naive patients with metastatic cutaneous melanoma.
حسب: Ranson, M, وآخرون
منشور في: (2007)

Computer interfacing with radial line slot arry (RLSA) antenna measurement /
حسب: 254621 Chin, Wen Sing
منشور في: (1999)

Monitoring and quantification of rural urbanisation: Case of Arris and Theniet Elabed, Algeria
حسب: Soto Sabrina, وآخرون
منشور في: (2024-01-01)

In search of an architectural genome of traditional houses: Case of the habitat of the Dechras of Arris
حسب: Aksas Samiha, وآخرون
منشور في: (2023-01-01)

581 Final analysis of 2-THE-TOP: a phase 2 study of TTFields (Optune) plus pembrolizumab plus maintenance temozolomide (TMZ) in patients with newly diagnosed glioblastoma
حسب: David Tran, وآخرون
منشور في: (2023-11-01)

High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment
حسب: Klaus Braun, Volker Ehemann, Manfred Wiessler, Ruediger Pipkorn, Bernd Didinger, Gabriele Mueller, Waldemar Waldeck
منشور في: (2009-01-01)

Fingerprint-fingervein multimodal biometric authentication system on field programmable gate arry /
حسب: Chong, Yew Hoe, 1992-, وآخرون
منشور في: (2015)

A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma.
حسب: Kefford, R, وآخرون
منشور في: (2009)

The Application of ATR Kinase Inhibitor AZD6738 in Combination with Radiotherapy for the Treatment of Melanoma
حسب: Maryam Talebpoor, وآخرون
منشور في: (2022-06-01)

Dual axis rotation solar irradiance tracking system for photovoltaic arry [electronic resource] /
حسب: Thanikaikumaran R. Kuppusamy, 1987-, author 646957, وآخرون
منشور في: (2017)

The phenomenon of repetition according to Abu Al-Ala’ Al-Ma’arri in “The Chapters and Ends”
حسب: زهره قرباني مادواني
منشور في: (2018-02-01)

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide
حسب: Ramcharan, R, وآخرون
منشور في: (2015)

Conce pts of statistical inference/
حسب: 216135 Guenther, William C.
منشور في: (1973)

Fingerprint-fingervein multimodal biometric authentication system on field programmable gate arry [electronic resource] /
حسب: Chong, Yew Hoe, 1992-, وآخرون
منشور في: (2015)

An optical wavelength multi/demultiplexing (DWDM/CWDM) based arry waveguide grating (AWG) technique /
حسب: 333366 Ismahayati Adam, وآخرون
منشور في: (2008)

KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells
حسب: Woessner Richard, وآخرون
منشور في: (2009-07-01)

637 INB-200: Phase I study of gene modified autologous gamma-delta (γδ) T cells in newly diagnosed glioblastoma (GBM) patients receiving maintenance temozolomide (TMZ): immunobiologic correlative data
حسب: Trishna Goswami, وآخرون
منشور في: (2023-11-01)

Clinical activity and safety of sintilimab, bevacizumab, and TMZ in patients with recurrent glioblastoma
حسب: Yinghao Lu, وآخرون
منشور في: (2024-01-01)

<b>Peroxidase activity in <em>Spondias dulcis</em></b> - 10.4025/actascitechnol.v32i4.6244
حسب: Dayse Pereira Barbosa Souza, وآخرون
منشور في: (2010-12-01)

Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group.
حسب: Gogas, H, وآخرون
منشور في: (2006)

Effects of temozolomide on tumor mutation burden and microsatellite instability in melanoma cells
حسب: M. Sawada, وآخرون
منشور في: (2024-01-01)

AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study

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