The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.
In this review, we describe the background and implications of our recent discovery that two-pore channels (TPCs) comprise a novel class of calcium release channels gated by the intracellular messenger nicotinic acid adenine dinucleotide phosphate (NAADP). Their localisation to the endolysosomal sys...
Täydet tiedot
Bibliografiset tiedot
Päätekijät: |
Galione, A,
Evans, A,
Ma, J,
Parrington, J,
Arredouani, A,
Cheng, X,
Zhu, M |
Aineistotyyppi: | Journal article
|
Kieli: | English |
Julkaistu: |
2009
|