Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1

The neoplastic transformation of cells and inflammation are processes that contribute to tumor initiation. Recently, emerging evidence has suggested that epigenetic alterations are also implicated in the early stages of carcinogenesis. Therefore, potent small molecules targeting epigenetic regulator...

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Bibliographic Details
Main Authors: Zhang, C, Su, Z, Wang, L, Shu, L, Yang, Y, Guo, Y, Pung, D, Bountra, C, Kong, A
Format: Journal article
Language:English
Published: Elsevier 2016