Structure and substrate specificity of the Pim-1 kinase.

Structure and substrate specificity of the Pim-1 kinase.

عرض إصدارات أخرى (1)

The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3) belonging to the CAMK (calmodulin-dependent protein kinase-related) group. Pim kinases are emerging as important mediators of cytokine signaling pathways in hematopoietic cells, and they contribute...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Bullock, A, Debreczeni, J, Amos, A, Knapp, S, Turk, B
التنسيق:	Journal article
اللغة:	English
منشور في:	2005

مواد مشابهة

Structure and substrate specificity of the Pim-1 kinase
حسب: Bullock, A, وآخرون
منشور في: (2005)

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.
حسب: Bullock, A, وآخرون
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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
حسب: Bullock, A, وآخرون
منشور في: (2009)

Ruthenium half-sandwich complexes bound to protein kinase Pim-1
حسب: Debreczeni, J, وآخرون
منشور في: (2006)

Ruthenium half-sandwich complexes bound to protein kinase Pim-1.
حسب: Debreczeni, J, وآخرون
منشور في: (2006)

Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
حسب: Alex N Bullock, وآخرون
منشور في: (2009-10-01)

Electrostatically Enhanced Association of a Pim Kinase Substrate Revealed by Stochastic Detection
حسب: Harrington, L, وآخرون
منشور في: (2014)

PIM1 kinase and its diverse substrate in solid tumors
حسب: Rituparna Choudhury, وآخرون
منشور في: (2024-11-01)

Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.
حسب: Pogacic, V, وآخرون
منشور في: (2007)

Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate.
حسب: Harrington, L, وآخرون
منشور في: (2013)

STUDYING THE ROLE OF PIM KINASES IN FLT3-ITD-INDUCED LEUKEMIA REVEALED PIM1 AS REGULATOR OF CXCL12/CXCR4-MEDIATED HOMING AND MIGRATION
حسب: Brault, L, وآخرون
منشور في: (2009)

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors.
حسب: Akué-Gédu, R, وآخرون
منشور في: (2009)

Crystal structure-guided design of bisubstrate inhibitors and photoluminiscent probes for protein kinases of the PIM family
حسب: Nonga, OE, وآخرون
منشور في: (2021)

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
حسب: López-Ramos, M, وآخرون
منشور في: (2010)

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
حسب: López-Ramos, M, وآخرون
منشور في: (2010)

Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration.
حسب: Grundler, R, وآخرون
منشور في: (2009)

Dissecting Proto-Oncogenic PIM Serine/Threonine Kinases in FLT3-ITD-Induced Leukemogenesis: PIM1 Regulates CXCL12/CXCR4-Mediated Homing and Migration
حسب: Gasser, C, وآخرون
منشور في: (2008)

Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure
حسب: Lori, C, وآخرون
منشور في: (2013)

Selective bisubstrate inhibitors with sub-nanomolar affinity for protein kinase Pim-1.
حسب: Ekambaram, R, وآخرون
منشور في: (2013)

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
حسب: Bullock, A, وآخرون
منشور في: (2009)

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation
حسب: Bullock, A, وآخرون
منشور في: (2009)

Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family
حسب: Olivier E. Nonga, وآخرون
منشور في: (2021-07-01)

Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure.
حسب: Clorinda Lori, وآخرون
منشور في: (2013-01-01)

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights (September, pg 3175, 2010)
حسب: Lopez-Ramos, M, وآخرون
منشور في: (2011)

Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture.
حسب: Eswaran, J, وآخرون
منشور في: (2008)

Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
حسب: Bataille, C, وآخرون
منشور في: (2017)

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers.
حسب: Brault, L, وآخرون
منشور في: (2010)

Targeting PIM Kinases to Improve the Efficacy of Immunotherapy
حسب: Amber N. Clements, وآخرون
منشور في: (2022-11-01)

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.
حسب: Brault, L, وآخرون
منشور في: (2012)

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma
حسب: Brault, L, وآخرون
منشور في: (2012)

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
حسب: Laurent Brault, وآخرون
منشور في: (2010-06-01)

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA.
حسب: Fang Cheng, وآخرون
منشور في: (2009-03-01)

Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity
حسب: Peltola Katriina J, وآخرون
منشور في: (2006-05-01)

An overview of pim kinase as a target in multiple myeloma
حسب: Zhaoyun Liu, وآخرون
منشور في: (2023-05-01)

Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
حسب: Rachel K. Toth, وآخرون
منشور في: (2022-03-01)

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.
حسب: Filippakopoulos, P, وآخرون
منشور في: (2008)

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.
حسب: Filippakopoulos, P, وآخرون
منشور في: (2008)

Molecular insights and inhibitory dynamics of flavonoids in targeting Pim-1 kinase for cancer therapy
حسب: Hani A. Alhadrami, وآخرون
منشور في: (2024-10-01)

New potent dual inhibitors of CK2 and Pim kinases: Discovery and structural insights (The FASEB Journal (2010) (3175) DOI: 10.1096/fj.09-143743)
حسب: López-Ramos, M, وآخرون
منشور في: (2011)

Human CD180 Transmits Signals via the PIM-1L Kinase.
حسب: Nicole Egli, وآخرون
منشور في: (2015-01-01)