Structure and substrate specificity of the Pim-1 kinase.

Structure and substrate specificity of the Pim-1 kinase.

Εμφάνιση άλλων εκδόσεων (1)

The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3) belonging to the CAMK (calmodulin-dependent protein kinase-related) group. Pim kinases are emerging as important mediators of cytokine signaling pathways in hematopoietic cells, and they contribute...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Bullock, A, Debreczeni, J, Amos, A, Knapp, S, Turk, B
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2005

Παρόμοια τεκμήρια

Structure and substrate specificity of the Pim-1 kinase
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Ruthenium half-sandwich complexes bound to protein kinase Pim-1.
ανά: Debreczeni, J, κ.ά.
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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
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ανά: López-Ramos, M, κ.ά.
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New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
ανά: López-Ramos, M, κ.ά.
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Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration.
ανά: Grundler, R, κ.ά.
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Dissecting Proto-Oncogenic PIM Serine/Threonine Kinases in FLT3-ITD-Induced Leukemogenesis: PIM1 Regulates CXCL12/CXCR4-Mediated Homing and Migration
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Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure
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Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.
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Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation
ανά: Bullock, A, κ.ά.
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Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family
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Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure.
ανά: Clorinda Lori, κ.ά.
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Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
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PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers.
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Targeting PIM Kinases to Improve the Efficacy of Immunotherapy
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PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.
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PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma
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PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
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KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA.
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Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity
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Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
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Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation.
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Human CD180 Transmits Signals via the PIM-1L Kinase.
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