Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis.

OBJECTIVE: To examine 11 candidate genes as susceptibility loci for osteoarthritis (OA). METHODS: A total of 481 families have been ascertained in which at least two siblings have had joint replacement surgery of the hip, or knee, or hip and knee for idiopathic OA. Each candidate gene was targeted...

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Hlavní autoři: Mustafa, Z, Chapman, K, Irven, C, Carr, A, Clipsham, K, Chitnavis, J, Sinsheimer, J, Bloomfield, V, McCartney, M, Cox, O, Sykes, B, Loughlin, J
Médium: Journal article
Jazyk:English
Vydáno: 2000