Common and rare variants in multifactorial susceptibility to common diseases.

Here, we give a historical overview of the search for genetic variants that influence the susceptibility of an individual to a chronic disease, from RA Fisher's seminal work to the current excitement of whole-genome association studies (WGAS). We then discuss the concepts behind the identificat...

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Những tác giả chính: Bodmer, W, Bonilla, C
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2008