No evidence for drug resistance by iminosugar-based HCV assembly inhibitors in tissue culture

No evidence for drug resistance by iminosugar-based HCV assembly inhibitors in tissue culture

At present, neither a selective antiviral therapy nor a vaccine is available for HCV, and the current treatment is only effective in a fraction of patients. Given the recent demonstration that antiviral compounds targeting the NS5B polymerase and the NS3/4A protease lead to rapid selection for resis...

書目詳細資料
Main Authors:	Steinmann, E, Friesland, M, Ciesek, S, Zitzmann, N, Pietschmann, T
格式:	Journal article
出版:	Elsevier 2010

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