Forward genetic analysis of mammalian immunity

Forward genetic analysis of mammalian immunity

<p>Mutation, whether spontaneous or induced, is the premier tool for understanding gene function. One approach is to create mutations in a specific gene, and then use the resulting cell or organism to search for a phenotype. An alternative is to create mutations at random, and focus first on t...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Siggs, O, Owen Siggs
Rannpháirtithe:	Beutler, B
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2012
Ábhair:	Immunology Genetics (life sciences)

Míreanna comhchosúla

Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5
de réir: Barnes, MJ
Foilsithe / Cruthaithe: (2010)

Dissecting mammalian immunity through mutation
de réir: Siggs, O
Foilsithe / Cruthaithe: (2014)

Dissecting mammalian immunity through mutation.
de réir: Siggs, O
Foilsithe / Cruthaithe: (2014)

Investigation of expression quantitative trait loci and regulatory genetic variants in primary human immune cells
de réir: Makino, S
Foilsithe / Cruthaithe: (2013)

Genetics determinants of vaccine responses
de réir: O'Connor, D
Foilsithe / Cruthaithe: (2014)

Impact of genetic variation on gene regulatory effects of vitamin D in immunity and inflammation
de réir: Berlanga-Taylor, A
Foilsithe / Cruthaithe: (2013)

Functional characterization of ankylosing spondylitis genetic risk variants
de réir: Osgood, JA
Foilsithe / Cruthaithe: (2019)

NOVEL LYMPHOCYTE DEFICIENCIES REVEALED BY MOUSE FORWARD GENETICS
de réir: Siggs, O, et al.
Foilsithe / Cruthaithe: (2012)

Genetic studies in ulcerative colitis
de réir: Bryant, RV
Foilsithe / Cruthaithe: (2015)

Immune Thrombocytopenia: Immune Dysregulation and Genetic Perturbations Deciphering the Fate of Platelets
de réir: Zahra Tariq, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Analyses of functional sequence in mammalian and avian genomes
de réir: Rands, C, et al.
Foilsithe / Cruthaithe: (2014)

Epigenetic regulation of the myeloid cell lineage
de réir: Pliuskys, L
Foilsithe / Cruthaithe: (2014)

Genetic association with autoimmune diseases identifies molecular mechanisms of coronary artery disease
de réir: Sophia Kerns, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice
de réir: Okiru Komine, et al.
Foilsithe / Cruthaithe: (2024-02-01)

Immunology : Mammalian watchdog targets bacteria
de réir: Kundu, Parag, et al.
Foilsithe / Cruthaithe: (2015)

Influence of genetic and environmental factors on the immunogenicity of Hib vaccine in Gambian twins
de réir: Lee, Y, et al.
Foilsithe / Cruthaithe: (2006)

An insight into osteoarthritis susceptibility: Integration of immunological and genetic background
de réir: Debora Stefik, et al.
Foilsithe / Cruthaithe: (2021-04-01)

Molecular genetics of mammalian cells/
de réir: Gottesma, Michael M.
Foilsithe / Cruthaithe: (1987)

The impact of genetic variation on IFITM3 related influenza virus restriction
de réir: Laurenson-Schafer, H
Foilsithe / Cruthaithe: (2018)

Functional characterisation of a multiple sclerosis-associated genetic variant
de réir: Gregory, A
Foilsithe / Cruthaithe: (2012)

Mammalian BEX, WEX and GASP genes: Coding and non-coding chimaerism sustained by gene conversion events
de réir: Winter, E, et al.
Foilsithe / Cruthaithe: (2005)

Investigating the genetic basis of autoimmune disease
de réir: Hodgson, R
Foilsithe / Cruthaithe: (2021)

The role of DOCK8 in the maintenance of CD8+ T cell memory and invariant NKT cells
de réir: Crawford, G
Foilsithe / Cruthaithe: (2012)

Analysis of the CD200R family
de réir: Akkaya, M
Foilsithe / Cruthaithe: (2011)

Allele specific gene expression in the major histocompatibility complex
de réir: Plant, K
Foilsithe / Cruthaithe: (2012)

The functional consequences of autoimmune variants in the tyrosine kinase 2 gene region
de réir: Shipman, L
Foilsithe / Cruthaithe: (2014)

Construction and validation of Plasmodium antigens surface display library in mammalian cells.
de réir: Tan, Li Hua.
Foilsithe / Cruthaithe: (2009)

Functional characterisation of multiple sclerosis-associated single nucleotide polymorphisms in the Eomesodermin region
de réir: Leach, O
Foilsithe / Cruthaithe: (2015)

Functional genomics of severe sepsis and septic shock
de réir: Radhakrishnan, J
Foilsithe / Cruthaithe: (2013)

Branches and Key Components of Genetics /
de réir: Linares, Marie, author 648628, et al.
Foilsithe / Cruthaithe: (2012)

Genetic determinants of EBV infection in lymphoblastoid cell lines
de réir: Czyz, W, et al.
Foilsithe / Cruthaithe: (2014)

History, Research and Key Concepts of Genetics /
de réir: Major, Jude, author 648645, et al.
Foilsithe / Cruthaithe: (2012)

Genetics of ankylosing spondylitis
de réir: Karaderi, T
Foilsithe / Cruthaithe: (2012)

Simple and highly specific targeting of resident microglia with adeno-associated virus
de réir: Carolina Serrano, et al.
Foilsithe / Cruthaithe: (2024-09-01)

NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics
de réir: Choi, Youngjoo, et al.
Foilsithe / Cruthaithe: (2024)

Identification of the cellular and molecular mechanisms of IL-23 driven intestinal inflammation
de réir: Schiering, C
Foilsithe / Cruthaithe: (2013)

Large-scale genetic analysis of quantitative traits
de réir: Randall, J, et al.
Foilsithe / Cruthaithe: (2012)

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
de réir: Arnold, C, et al.
Foilsithe / Cruthaithe: (2012)

De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency
de réir: Marina Villamor-Payà, et al.
Foilsithe / Cruthaithe: (2024-06-01)

T cell hybrid immunity against SARS-CoV-2 in children: a longitudinal study
de réir: Qui, Martin, et al.
Foilsithe / Cruthaithe: (2024)