Recurrent genetic defects on chromosome 5q in myeloid neoplasms

Recurrent genetic defects on chromosome 5q in myeloid neoplasms

BACKGROUND: Deletion of chromosome 5q (del(5q)) is the most common karyotypic abnormality in myeloid neoplasms. MATERIALS AND METHODS: To define the pathogenic molecular features associated with del(5q), next-generation sequencing was applied to 133 patients with myeloid neoplasms (MDS; N = 69, MDS/...

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Main Authors: Hosono, N, Makishima, H, Mahfouz, R, Przychodzen, B, Yoshida, K, Jerez, A, LaFramboise, T, Polprasert, C, Clemente, M, Shiraishi, Y, Chiba, K, Tanaka, H, Miyano, S, Sanada, M, Cui, E, Verma, A, McDevitt, M, List, A, Saunthararajah, Y, Sekeres, M, Boultwood, J, Ogawa, S, Maciejewski, J
Format: Journal article
Language:English
Published: Impact Journals 2016

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