role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes
The role of the Na+/Ca2+ exchanger (NCX) as the main pathway for Ca2+ extrusion from ventricular myocytes is well established. However, both the role of the Ca2+ entry mode of NCX in regulating local Ca2+ dynamics and the role or the Ca2+ exit mode during the majority of the physiological action pot...
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Format: | Journal article |
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2015
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author | Sher, A Noble, P Hinch, R Gavaghan, D Noble, D |
author_facet | Sher, A Noble, P Hinch, R Gavaghan, D Noble, D |
author_sort | Sher, A |
collection | OXFORD |
description | The role of the Na+/Ca2+ exchanger (NCX) as the main pathway for Ca2+ extrusion from ventricular myocytes is well established. However, both the role of the Ca2+ entry mode of NCX in regulating local Ca2+ dynamics and the role or the Ca2+ exit mode during the majority of the physiological action potential (AP) are subjects of controversy. The functional significance of NCXs location in T-tubules and potential co-l |
first_indexed | 2024-03-07T04:20:33Z |
format | Journal article |
id | oxford-uuid:cadf04ce-96db-45c0-ba60-a272163b4455 |
institution | University of Oxford |
last_indexed | 2024-03-07T04:20:33Z |
publishDate | 2015 |
record_format | dspace |
spelling | oxford-uuid:cadf04ce-96db-45c0-ba60-a272163b44552022-03-27T07:10:37Zrole of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:cadf04ce-96db-45c0-ba60-a272163b4455Department of Computer Science2015Sher, ANoble, PHinch, RGavaghan, DNoble, DThe role of the Na+/Ca2+ exchanger (NCX) as the main pathway for Ca2+ extrusion from ventricular myocytes is well established. However, both the role of the Ca2+ entry mode of NCX in regulating local Ca2+ dynamics and the role or the Ca2+ exit mode during the majority of the physiological action potential (AP) are subjects of controversy. The functional significance of NCXs location in T-tubules and potential co-l |
spellingShingle | Sher, A Noble, P Hinch, R Gavaghan, D Noble, D role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes |
title | role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes |
title_full | role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes |
title_fullStr | role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes |
title_full_unstemmed | role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes |
title_short | role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes |
title_sort | role of the na ca2 exchangers in ca2 dynamics in ventricular myocytes |
work_keys_str_mv | AT shera roleofthenaca2exchangersinca2dynamicsinventricularmyocytes AT noblep roleofthenaca2exchangersinca2dynamicsinventricularmyocytes AT hinchr roleofthenaca2exchangersinca2dynamicsinventricularmyocytes AT gavaghand roleofthenaca2exchangersinca2dynamicsinventricularmyocytes AT nobled roleofthenaca2exchangersinca2dynamicsinventricularmyocytes |