Tau depletion in human neurons mitigates Aβ-driven toxicity
Alzheimer’s disease (AD) is an age-related neurodegenerative condition and the most common type of dementia, characterised by pathological accumulation of extracellular plaques and intracellular neurofibrillary tangles that mainly consist of amyloid-β (Aβ) and hyperphosphorylated tau aggregates, res...
Main Authors: | Ng, B, Vowles, J, Bertherat, F, Abey, A, Kilfeather, P, Beccano-Kelly, D, Stefana, MI, O’Brien, DP, Bengoa-Vergniory, N, Carling, PJ, Todd, JA, Caffrey, TM, Connor-Robson, N, Cowley, SA, Wade-Martins, R |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature [academic journals on nature.com]
2024
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