Differential effect of lactate on synovial fibroblast and macrophage effector functions
<p><strong>Introduction:</strong> The synovial membrane is the main site of inflammation in rheumatoid arthritis (RA). Here several subsets of fibroblasts and macrophages, with distinct effector functions, have been recently identified. The RA synovium is hypoxic and acidi...
Main Authors: | Pucino, V, Nefla, M, Gauthier, V, Alsaleh, G, Clayton, SA, Marshall, J, Filer, A, Clark, AR, Raza, K, Buckley, CD |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2023
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