Impaired proliferation and migration in human Miller-Dieker neural precursors.

Impaired proliferation and migration in human Miller-Dieker neural precursors.

OBJECTIVE: Miller-Dieker syndrome (MDS) is a malformation of cortical development that results in lissencephaly (meaning smooth brain). This disorder is caused by heterozygous deletions on chromosome 17p13.3, including the lissencephaly 1 (LIS1) gene. Various mouse models have been used as an exper...

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Bibliographic Details
Main Authors: Sheen, V, Ferland, R, Harney, M, Hill, R, Neal, J, Banham, A, Brown, P, Chenn, A, Corbo, J, Hecht, J, Folkerth, R, Walsh, C
Format: Journal article
Language:English
Published: 2006

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