Collagen-induced arthritis in mice: a major role for tumor necrosis factor-alpha.

Collagen-induced arthritis is the most widely used animal model for the evaluation of novel therapeutic strategies for rheumatoid arthritis. The disease is induced by immunization of genetically susceptible strains of mice or rats with type II collagen in adjuvant. Susceptibility to collagen-induced...

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Bibliographic Details
Main Author: Williams, R
Format: Journal article
Language:English
Published: 2007

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