Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.

Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.

Selective serotonin (5-HT) re-uptake inhibitors (SSRIs) are commonly used in the treatment of generalized anxiety disorder in Humans. However, because only few animal models display overt anxious-like behavior, detailed preclinical studies of the anxiolytic properties of antidepressants are still la...

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Autors principals:	Guilloux, J, David, D, Xia, L, Nguyen, H, Rainer, Q, Guiard, B, Repérant, C, Deltheil, T, Toth, M, Hen, R, Gardier, A
Format:	Journal article
Idioma:	English
Publicat:	2011

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