Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation.

Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation.

BACKGROUND: X chromosome inactivation, the mechanism used by mammals to equalise dosage of X-linked genes in XX females relative to XY males, is triggered by chromosome-wide localisation of a cis-acting non-coding RNA, Xist. The mechanism of Xist RNA spreading and Xist-dependent silencing is poorly...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Tang, Y, Huntley, D, Montana, G, Cerase, A, Nesterova, T, Brockdorff, N
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2010

Eitemau Tebyg

Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation
gan: Tang Y Amy, et al.
Cyhoeddwyd: (2010-05-01)

Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
gan: Ikrame Naciri, et al.
Cyhoeddwyd: (2021-06-01)

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to establish polycomb-mediated chromosomal silencing
gan: Pintacuda, G, et al.
Cyhoeddwyd: (2017)

Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation.
gan: Senner, C, et al.
Cyhoeddwyd: (2011)

Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations
gan: Agnese Loda, et al.
Cyhoeddwyd: (2017-09-01)

Advances in understanding chromosome silencing by the long non-coding RNA Xist.
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Cyhoeddwyd: (2013)

YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing
gan: Bowness, JS, et al.
Cyhoeddwyd: (2024)

A pooled shRNA screen identifies Rbm15, Spen, and Wtap as factors required for Xist RNA-mediated silencing
gan: Moindrot, B, et al.
Cyhoeddwyd: (2015)

Localized accumulation of Xist RNA in X chromosome inactivation
gan: Neil Brockdorff
Cyhoeddwyd: (2019-12-01)

Xist Repeats B and C, but not Repeat A, mediate de novo recruitment of the Polycomb system in X chromosome inactivation
gan: Wei, G, et al.
Cyhoeddwyd: (2021)

Study of Xist-mediated gene silencing using iXist
gan: Tan, Jin Da
Cyhoeddwyd: (2015)

The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation
gan: Coker, H, et al.
Cyhoeddwyd: (2020)

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.
gan: Mariana de Napoles, et al.
Cyhoeddwyd: (2007-09-01)

Functional analysis of Xist-mediated silencing
gan: Pintacuda, G
Cyhoeddwyd: (2016)

Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
gan: Bowness, JS, et al.
Cyhoeddwyd: (2022)

Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
gan: Joseph S. Bowness, et al.
Cyhoeddwyd: (2022-05-01)

Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.
gan: Shevchenko, A, et al.
Cyhoeddwyd: (2011)

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy.
gan: Cerase, A, et al.
Cyhoeddwyd: (2014)

The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.
gan: Hasegawa, Y, et al.
Cyhoeddwyd: (2010)

Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.
gan: Alexander I Shevchenko, et al.
Cyhoeddwyd: (2011-01-01)

Active chromatin marks are retained on X chromosomes lacking gene or repeat silencing despite XIST/Xist expression in somatic cell hybrids.
gan: Nancy P Thorogood, et al.
Cyhoeddwyd: (2010-05-01)

Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns.
gan: Brockdorff, N
Cyhoeddwyd: (2011)

Xist gene regulation at the onset of X inactivation.
gan: Senner, C, et al.
Cyhoeddwyd: (2009)

Early chromosome condensation by XIST builds A-repeat RNA density that facilitates gene silencing
gan: Melvys Valledor, et al.
Cyhoeddwyd: (2023-07-01)

Stochastic gene expression and chromosome interactions in protecting the human active X from silencing by XIST
gan: Barbara R. Migeon
Cyhoeddwyd: (2021-01-01)

The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation [version 1; peer review: 1 approved, 2 approved with reservations]
gan: Heather Coker, et al.
Cyhoeddwyd: (2020-02-01)

The nuclear matrix protein CIZ1 facilitates localisation of Xist RNA to the inactive X-chromosome territory
gan: Ridings-Figueroa, R, et al.
Cyhoeddwyd: (2017)

Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome.
gan: Norishige Yamada, et al.
Cyhoeddwyd: (2015-08-01)

Function by Structure: Spotlights on Xist Long Non-coding RNA
gan: Greta Pintacuda, et al.
Cyhoeddwyd: (2017-12-01)

Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells.
gan: Nesterova, T, et al.
Cyhoeddwyd: (2011)

Xist at the edge: silencing at the nuclear periphery extends to X inactivation
gan: Demmerle, J, et al.
Cyhoeddwyd: (2016)

Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a.
gan: Nesterova, T, et al.
Cyhoeddwyd: (2008)

The role of Xist RNA in the maintenance of X chromosome inactivation
gan: Csankovszki, Györgyi, 1971-
Cyhoeddwyd: (2005)

Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals.
gan: Julie Chaumeil, et al.
Cyhoeddwyd: (2011-01-01)

Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression
gan: Andrea Cerase, et al.
Cyhoeddwyd: (2021-04-01)

Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
gan: Rodermund, L, et al.
Cyhoeddwyd: (2021)

Pluripotency factor binding and <it>Tsix </it>expression act synergistically to repress <it>Xist </it>in undifferentiated embryonic stem cells
gan: Nesterova Tatyana B, et al.
Cyhoeddwyd: (2011-10-01)

A study on X chromosome reactivation using iXist
gan: Lai, Lan Tian
Cyhoeddwyd: (2017)

CIZ1 in Xist seeded assemblies at the inactive X chromosome
gan: Sajad Sofi, et al.
Cyhoeddwyd: (2023-12-01)

RNF12 activates Xist and is essential for X chromosome inactivation.
gan: Tahsin Stefan Barakat, et al.
Cyhoeddwyd: (2011-01-01)