Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation.

Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation.

BACKGROUND: X chromosome inactivation, the mechanism used by mammals to equalise dosage of X-linked genes in XX females relative to XY males, is triggered by chromosome-wide localisation of a cis-acting non-coding RNA, Xist. The mechanism of Xist RNA spreading and Xist-dependent silencing is poorly...

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Bibliografiske detaljer
Main Authors:	Tang, Y, Huntley, D, Montana, G, Cerase, A, Nesterova, T, Brockdorff, N
Format:	Journal article
Sprog:	English
Udgivet:	2010

Lignende værker

Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation
af: Tang Y Amy, et al.
Udgivet: (2010-05-01)

Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
af: Ikrame Naciri, et al.
Udgivet: (2021-06-01)

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to establish polycomb-mediated chromosomal silencing
af: Pintacuda, G, et al.
Udgivet: (2017)

Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation.
af: Senner, C, et al.
Udgivet: (2011)

Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations
af: Agnese Loda, et al.
Udgivet: (2017-09-01)

Advances in understanding chromosome silencing by the long non-coding RNA Xist.
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Udgivet: (2013)

YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing
af: Bowness, JS, et al.
Udgivet: (2024)

A pooled shRNA screen identifies Rbm15, Spen, and Wtap as factors required for Xist RNA-mediated silencing
af: Moindrot, B, et al.
Udgivet: (2015)

Localized accumulation of Xist RNA in X chromosome inactivation
af: Neil Brockdorff
Udgivet: (2019-12-01)

Xist Repeats B and C, but not Repeat A, mediate de novo recruitment of the Polycomb system in X chromosome inactivation
af: Wei, G, et al.
Udgivet: (2021)

Study of Xist-mediated gene silencing using iXist
af: Tan, Jin Da
Udgivet: (2015)

The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation
af: Coker, H, et al.
Udgivet: (2020)

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.
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Udgivet: (2007-09-01)

Functional analysis of Xist-mediated silencing
af: Pintacuda, G
Udgivet: (2016)

Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
af: Bowness, JS, et al.
Udgivet: (2022)

Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
af: Joseph S. Bowness, et al.
Udgivet: (2022-05-01)

Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.
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Udgivet: (2011)

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy.
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Udgivet: (2014)

The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.
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Udgivet: (2010)

Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.
af: Alexander I Shevchenko, et al.
Udgivet: (2011-01-01)

Active chromatin marks are retained on X chromosomes lacking gene or repeat silencing despite XIST/Xist expression in somatic cell hybrids.
af: Nancy P Thorogood, et al.
Udgivet: (2010-05-01)

Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns.
af: Brockdorff, N
Udgivet: (2011)

Xist gene regulation at the onset of X inactivation.
af: Senner, C, et al.
Udgivet: (2009)

Early chromosome condensation by XIST builds A-repeat RNA density that facilitates gene silencing
af: Melvys Valledor, et al.
Udgivet: (2023-07-01)

Stochastic gene expression and chromosome interactions in protecting the human active X from silencing by XIST
af: Barbara R. Migeon
Udgivet: (2021-01-01)

The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation [version 1; peer review: 1 approved, 2 approved with reservations]
af: Heather Coker, et al.
Udgivet: (2020-02-01)

The nuclear matrix protein CIZ1 facilitates localisation of Xist RNA to the inactive X-chromosome territory
af: Ridings-Figueroa, R, et al.
Udgivet: (2017)

Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome.
af: Norishige Yamada, et al.
Udgivet: (2015-08-01)

Function by Structure: Spotlights on Xist Long Non-coding RNA
af: Greta Pintacuda, et al.
Udgivet: (2017-12-01)

Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells.
af: Nesterova, T, et al.
Udgivet: (2011)

Xist at the edge: silencing at the nuclear periphery extends to X inactivation
af: Demmerle, J, et al.
Udgivet: (2016)

Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a.
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Udgivet: (2008)

The role of Xist RNA in the maintenance of X chromosome inactivation
af: Csankovszki, Györgyi, 1971-
Udgivet: (2005)

Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals.
af: Julie Chaumeil, et al.
Udgivet: (2011-01-01)

Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression
af: Andrea Cerase, et al.
Udgivet: (2021-04-01)

Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
af: Rodermund, L, et al.
Udgivet: (2021)

Pluripotency factor binding and <it>Tsix </it>expression act synergistically to repress <it>Xist </it>in undifferentiated embryonic stem cells
af: Nesterova Tatyana B, et al.
Udgivet: (2011-10-01)

A study on X chromosome reactivation using iXist
af: Lai, Lan Tian
Udgivet: (2017)

CIZ1 in Xist seeded assemblies at the inactive X chromosome
af: Sajad Sofi, et al.
Udgivet: (2023-12-01)

RNF12 activates Xist and is essential for X chromosome inactivation.
af: Tahsin Stefan Barakat, et al.
Udgivet: (2011-01-01)