Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation.
BACKGROUND: X chromosome inactivation, the mechanism used by mammals to equalise dosage of X-linked genes in XX females relative to XY males, is triggered by chromosome-wide localisation of a cis-acting non-coding RNA, Xist. The mechanism of Xist RNA spreading and Xist-dependent silencing is poorly...
Автори: | Tang, Y, Huntley, D, Montana, G, Cerase, A, Nesterova, T, Brockdorff, N |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2010
|
Схожі ресурси
Схожі ресурси
-
Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation
за авторством: Tang Y Amy, та інші
Опубліковано: (2010-05-01) -
Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
за авторством: Ikrame Naciri, та інші
Опубліковано: (2021-06-01) -
hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to establish polycomb-mediated chromosomal silencing
за авторством: Pintacuda, G, та інші
Опубліковано: (2017) -
Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation.
за авторством: Senner, C, та інші
Опубліковано: (2011) -
Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations
за авторством: Agnese Loda, та інші
Опубліковано: (2017-09-01)