Cutaneous squamous cell carcinoma (SCC) and the DNA damage response: pATM expression patterns in pre-malignant and malignant keratinocyte skin lesions.
Recent evidence suggests that an initial barrier to the emergence of tumours is a DNA damage response that evokes a counter-response which arrests the growth of, or eliminates, damaged cells. Early precursor lesions express markers of an activated DNA damage response in several types of tumour, with...
Main Authors: | Ismail, F, Ikram, M, Purdie, K, Harwood, C, Leigh, I, Storey, A |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2011
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