Cutaneous squamous cell carcinoma (SCC) and the DNA damage response: pATM expression patterns in pre-malignant and malignant keratinocyte skin lesions.

Recent evidence suggests that an initial barrier to the emergence of tumours is a DNA damage response that evokes a counter-response which arrests the growth of, or eliminates, damaged cells. Early precursor lesions express markers of an activated DNA damage response in several types of tumour, with...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ismail, F, Ikram, M, Purdie, K, Harwood, C, Leigh, I, Storey, A
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2011