Cutaneous squamous cell carcinoma (SCC) and the DNA damage response: pATM expression patterns in pre-malignant and malignant keratinocyte skin lesions.

Recent evidence suggests that an initial barrier to the emergence of tumours is a DNA damage response that evokes a counter-response which arrests the growth of, or eliminates, damaged cells. Early precursor lesions express markers of an activated DNA damage response in several types of tumour, with...

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Détails bibliographiques
Auteurs principaux: Ismail, F, Ikram, M, Purdie, K, Harwood, C, Leigh, I, Storey, A
Format: Journal article
Langue:English
Publié: Public Library of Science 2011