Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety. Protocol for a systematic review
<p>Introduction. Gabapentin has been extensively prescribed off-label for psychiatric indications, with little established evidence of efficacy. Both gabapentin and pregabalin, a very similar drug with the same mechanism of action, bind to a subunit of voltage dependent calcium channels, which...
Main Authors: | Houghton, K, Forrest, A, Awad, A, Cipriani, A, Atkinson, L, Stockton, S, Harrison, P, Geddes, J |
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Format: | Journal article |
Published: |
BMJ Publishing Group
2017
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