Concentration-dependent mortality of chloroquine in overdose

Concentration-dependent mortality of chloroquine in overdose

Hydroxychloroquine and chloroquine are used extensively in malaria and rheumatological conditions, and now in COVID-19 prevention and treatment. Although generally safe they are potentially lethal in overdose. In-vitro data suggest that high concentrations and thus high doses are needed for COVID-19...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Watson, JA, Tarning, J, Hoglund, RM, Baud, FJ, Megarbane, B, Clemessy, J-L, White, NJ
Materialtyp:	Journal article
Språk:	English
Publicerad:	eLife Sciences Publications 2020

Liknande verk

Concentration-dependent mortality of chloroquine in overdose
av: James A Watson, et al.
Publicerad: (2020-07-01)

Pharmacometric and electrocardiographic evaluation of chloroquine and azithromycin in healthy volunteers
av: Chotsiri, P, et al.
Publicerad: (2022)

COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology
av: White, NJ, et al.
Publicerad: (2020)

Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine
av: Ippolito, M, et al.
Publicerad: (2018)

COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology.
av: Nicholas J White, et al.
Publicerad: (2020-09-01)

A Case Report of Suicide with Chloroquine Overdose and Review of Literature
av: Maryam Hosseini, et al.
Publicerad: (2016-08-01)

A Case Report of Suicide with Chloroquine Overdose and Review of Literature
av: Maryam Hosseini, et al.
Publicerad: (2016-09-01)

Toxic psychosis due to chloroquine overdose : a case report
av: Syed Ahmed Zaki, et al.
Publicerad: (2009-02-01)

Mechanistic modeling of primaquine pharmacokinetics, gametocytocidal activity, and mosquito infectivity
av: Chotsiri, P, et al.
Publicerad: (2022)

Pharmacokinetic interactions between primaquine and chloroquine.
av: Pukrittayakamee, S, et al.
Publicerad: (2014)

Comparison of the umulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in Plasmodium vivax malaria
av: Chu, C, et al.
Publicerad: (2018)

Comparison of the cumulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in plasmodium vivax malaria
av: Chu, C, et al.
Publicerad: (2018)

Plasma chloroquine concentrations in young and older malaria patients treated with chloroquine.
av: Maitland, K, et al.
Publicerad: (1997)

Management of Chloroquine and Hydroxychloroquine Poisoning: Do Not Miss the Time of Tracheal Intubation and Mechanical Ventilation
av: Bruno Megarbane, et al.
Publicerad: (2020-12-01)

Transmission-blocking activities of artesunate, chloroquine, and methylene blue on Plasmodium vivax gametocytes
av: Chaumeau, V, et al.
Publicerad: (2024)

Failure of chloroquine-erythromycin and chloroquine-tetracycline combinations in treatment of chloroquine-resistant falciparum malaria in eastern Thailand.
av: Phillips, R, et al.
Publicerad: (1984)

Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era
av: Watson, JA, et al.
Publicerad: (2021)

Chloroquine for donated blood?
av: White, N
Publicerad: (1987)

Chloroquine sulphate and chloroquine phosphate (chloroquine diphosphate)
av: 982 SIRIM

Plasma concentrations and toxicity of chloroquine after slow intravenous infusion in patients with falciparum malaria.
av: Edwards, G, et al.
Publicerad: (1987)

State marijuana laws and opioid overdose mortality
av: Stanford Chihuri, et al.
Publicerad: (2019-09-01)

Treatment of chloroquine-resistant Plasmodium vivax with chloroquine and primaquine or halofantrine.
av: Baird, J, et al.
Publicerad: (1995)

The treatment of chloroquine-resistant malaria.
av: van Vugt, M, et al.
Publicerad: (1999)

Whole blood chloroquine concentrations with Plasmodium vivax infection in Irian Jaya, Indonesia.
av: Baird, J, et al.
Publicerad: (1997)

Characterising blood stage antimalarial drug minimum inhibitory concentrations in vivo using reinfection patterns
av: Watson, J, et al.
Publicerad: (2018)

Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria.
av: White, N, et al.
Publicerad: (1989)

Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues
av: Wilian A. Cortopassi, et al.
Publicerad: (2022-12-01)

Investigation of the Mechanisms of Tramadol-Induced Seizures in Overdose in the Rat
av: Camille Lagard, et al.
Publicerad: (2022-10-01)

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers
av: Tarning, J, et al.
Publicerad: (2024)

Acetaminophen overdose associated with double serum concentration peaks
av: Cristian Papazoglu, et al.
Publicerad: (2015-12-01)

Population pharmacokinetic modelling of primaquine exposures in lactating women and breastfed infants
av: Wattanakul, T, et al.
Publicerad: (2024)

Enhancing timeliness of drug overdose mortality surveillance: A machine learning approach.
av: Patrick J Ward, et al.
Publicerad: (2019-01-01)

“Tranq-dope” overdose and mortality: lethality induced by fentanyl and xylazine
av: Mark A. Smith, et al.
Publicerad: (2023-10-01)

Variation of the Chloroquine Resistance Transporter (Crt) Gene in Chloroquine-Resistant and Chloroquine-Sensitive Plasmodium berghei
av: N Ghobakhloo, et al.
Publicerad: (2008-12-01)

Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications.
av: Krishna, S, et al.
Publicerad: (1996)

Parenteral chloroquine for treating falciparum malaria.
av: White, N, et al.
Publicerad: (1987)

Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels.
av: Baird, J, et al.
Publicerad: (1997)

Chloroquine sensitivity of Plasmodium vivax in Thailand.
av: Looareesuwan, S, et al.
Publicerad: (1999)

Assessment of factors affecting mortality in geriatric patients with warfarin overdose
av: Seda Dagar, et al.
Publicerad: (2020-01-01)

Comparison of artemether and chloroquine for severe malaria in Gambian children.
av: White, N, et al.
Publicerad: (1992)