Concentration-dependent mortality of chloroquine in overdose

Hydroxychloroquine and chloroquine are used extensively in malaria and rheumatological conditions, and now in COVID-19 prevention and treatment. Although generally safe they are potentially lethal in overdose. In-vitro data suggest that high concentrations and thus high doses are needed for COVID-19...

Description complète

Détails bibliographiques
Auteurs principaux: Watson, JA, Tarning, J, Hoglund, RM, Baud, FJ, Megarbane, B, Clemessy, J-L, White, NJ
Format: Journal article
Langue:English
Publié: eLife Sciences Publications 2020