Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide.

ATP-sensitive potassium (K(ATP)) channels are under complex regulation by intracellular ATP and ADP. The potentiatory effect of MgADP is conferred by the sulfonylurea receptor subunit of the channel, SUR, whereas the inhibitory effect of ATP appears to be mediated via the pore-forming subunit, Kir6....

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Hlavní autoři: Tanabe, K, Tucker, S, Ashcroft, F, Proks, P, Kioka, N, Amachi, T, Ueda, K
Médium: Journal article
Jazyk:English
Vydáno: 2000