Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood.
Neuregulin-1 (NRG1) plays a crucial role in axoglial signaling during the development of the peripheral nervous system, but its importance in adulthood after peripheral nerve injury remains unclear. We used single-neuron labeling with inducible Cre-mediated knock-out animals, which enabled visualiza...
Hlavní autoři: | Fricker, F, Lago, N, Balarajah, S, Tsantoulas, C, Tanna, S, Zhu, N, Fageiry, S, Jenkins, M, Garratt, A, Birchmeier, C, Bennett, D |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2011
|
Podobné jednotky
-
AXONAL NEUREGULIN-1 IS RATE LIMITING BUT NOT ESSENTIAL FOR PERIPHERAL NERVE REMYELINATION
Autor: Fricker, F, a další
Vydáno: (2013) -
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.
Autor: Fricker, F, a další
Vydáno: (2013) -
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.
Autor: Fricker, F, a další
Vydáno: (2009) -
The role of neuregulin-1 in the response to nerve injury.
Autor: Fricker, F, a další
Vydáno: (2011) -
Neuregulin-ErbB signaling promotes microglial proliferation and chemotaxis contributing to microgliosis and pain after peripheral nerve injury.
Autor: Calvo, M, a další
Vydáno: (2010)