The p53 response: a new mitochondrial role for cofactor strap
<p>Strap is a DNA damage responsive p53 cofactor, reflecting its control by the DNA damage signalling pathway. This study identified Strap at the mitochondria where it is damage regulated and can augment p53-dependent cytochrome c release leading to apoptosis. Moreover, p53 and Strap facilitat...
Үндсэн зохиолч: | Maniam, S |
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Бусад зохиолчид: | La Thangue, N |
Формат: | Дипломын ажил |
Хэл сонгох: | English |
Хэвлэсэн: |
2013
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Нөхцлүүд: |
Ижил төстэй зүйлс
Ижил төстэй зүйлс
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Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.
-н: Maniam, S, зэрэг
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Cofactor strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase
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ATM and Chk2 kinase target the p53 cofactor Strap.
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The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.
-н: Adams, C, зэрэг
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Nucleophosmin and p14ARF mediated regulation of p53
-н: Abraham, A
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