The p53 response: a new mitochondrial role for cofactor strap
<p>Strap is a DNA damage responsive p53 cofactor, reflecting its control by the DNA damage signalling pathway. This study identified Strap at the mitochondria where it is damage regulated and can augment p53-dependent cytochrome c release leading to apoptosis. Moreover, p53 and Strap facilitat...
第一著者: | Maniam, S |
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その他の著者: | La Thangue, N |
フォーマット: | 学位論文 |
言語: | English |
出版事項: |
2013
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主題: |
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