The p53 response: a new mitochondrial role for cofactor strap

<p>Strap is a DNA damage responsive p53 cofactor, reflecting its control by the DNA damage signalling pathway. This study identified Strap at the mitochondria where it is damage regulated and can augment p53-dependent cytochrome c release leading to apoptosis. Moreover, p53 and Strap facilitat...

Täydet tiedot

Bibliografiset tiedot
Päätekijä: Maniam, S
Muut tekijät: La Thangue, N
Aineistotyyppi: Opinnäyte
Kieli:English
Julkaistu: 2013
Aiheet: