Rapid generation of markerless recombinant MVA vaccines by en passant recombineering of a self-excising bacterial artificial chromosome.

The non-replicating poxviral vector modified vaccinia virus Ankara (MVA) is currently a leading candidate for development of novel recombinant vaccines against globally important diseases. The 1980s technology for making recombinant MVA (and other poxviruses) is powerful and robust, but relies on ra...

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Príomhchruthaitheoirí: Cottingham, MG, Gilbert, S
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2010

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