Dystrophin- and MLP-deficient mouse hearts: marked differences in morphology and function, but similar accumulation of cytoskeletal proteins.

In humans, cytoskeletal dystrophin and muscle LIM protein (MLP) gene mutations can cause dilated cardiomyopathy, yet these mutations may have different effects in mice, owing to increased accumulation of other, compensatory cytoskeletal proteins. Consequently, we characterized left-ventricular (LV)...

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Autors principals: Wilding, JR, Schneider, J, Sang, A, Davies, K, Neubauer, S, Clarke, K
Format: Journal article
Idioma:English
Publicat: 2005