Increased global transcription activity as a mechanism of replication stress in cancer

Cancer is a disease associated with genomic instability that often results from oncogene activation. This in turn leads to hyperproliferation and replication stress. However, the molecular mechanisms that underlie oncogene-induced replication stress are still poorly understood. Oncogenes such as HRA...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Kotsantis, P, Silva, L, Irmscher, S, Jones, R, Folkes, L, Gromak, N, Petermann, E
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Nature Publishing Group 2016

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