A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

Precision medicine in immune-mediated inflammatory diseases (IMIDs) requires a cellular understanding of treatment response. We describe a therapeutic atlas for Crohn’s disease (CD) and ulcerative colitis (UC) following adalimumab, an anti-tumour necrosis factor (anti-TNF) treatment. We generated ~1...

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Main Authors: Thomas, T, Friedrich, M, Rich-Griffin, C, Pohin, M, Agarwal, D, Pakpoor, J, Lee, C, Tandon, R, Rendek, A, Aschenbrenner, D, Jainarayanan, A, Voda, A, Siu, JHY, Sanches-Peres, R, Nee, E, Sathananthan, D, Kotliar, D, Todd, P, Kiourlappou, M, Gartner, L, Ilott, N, Issa, F, Hester, J, Turner, J, Mackerodt, J, Marsden, B, Taylor, S, Coles, M, Jostins-Dean, L, Powrie, FM, Travis, S, Uhlig, HH, Dendrou, CA, Buckley, CD
Format: Journal article
Language:English
Published: Nature Research 2024

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